Postdoctoral Research Scholar
North Carolina State University at Raleigh Raleigh, NC
The Physics Department provides: (1) High quality Physics instruction to the University community through courses in introductory physics; (2) educational opportunities for undergraduate and graduate students in physics through high quality curricula, faculty, and research facilities; (3) outreach programs that advance scientific knowledge. Our research programs cover a wide spectrum including astrophysics, general relativity, condensed matter theory and experiment, computational physics, biophysics, nanoscale science, physics education, experimental nuclear physics, particle and nuclear theory, experimental optics, and experimental atomic and molecular physics. The department enrolls approximately 120 graduate students and 140 undergrad physics majors. The department size is approximately 56 faculty members. While working in this department, you will be expected to foster a supportive and welcoming environment.
NC State promotes an integrated approach to problem solving that transforms lives and provides leadership for social, economic, and technological development across North Carolina and around the world. NC State’s land grant mission of teaching, research and service is dedicated to the service of North Carolina and its people. Applicants are encouraged to review the institution’s mission, vision and strategic plan, and consider how their background, interest and experience would enable them to support the university.
Duties and Responsibilities:
NC State promotes an integrated approach to problem solving that transforms lives and provides leadership for social, economic, and technological development across North Carolina and around the world. NC State’s land grant mission of teaching, research and service is dedicated to the service of North Carolina and its people. Applicants are encouraged to review the institution’s mission, vision and strategic plan, and consider how their background, interest and experience would enable them to support the university.
Duties and Responsibilities:
- Predictive modeling and design of protein–nucleic acid interactions, including protein–DNA recognition, protein–RNA interactions, and protein- or small-molecule binding to oligonucleotide aptamers, in close collaboration with experimental groups
- Physics-based and AI-enabled modeling of chromatin organization, RNA conformational dynamics, and RNA–protein phase separation.
- Depending on the scholar’s background, the research may emphasize bimolecular simulation, AI for bimolecular science, or an integrated combination of both.
- Responsibilities will include computational method development, rigorous validation against experimental data, development of reproducible software and workflows, manuscript preparation, and dissemination of research findings.
- Conduct independent and collaborative computational research on bimolecular structure, dynamics, interactions, and functions.
- Develop, implement, and evaluate molecular simulation and/or deep-learning methods; construct and analyze atomistic or coarse-grained models; integrate structural, sequence, thermodynamic, and experimental data; and perform rigorous statistical and mechanistic analyses.
- Research may address protein–DNA and protein–RNA recognition, aptamer binding and design, RNA conformational ensembles and dynamics, RNA–protein phase separation, and chromatin organization.
- Maintain reproducible, well-documented software and workflows, communicate findings through peer-reviewed publications, conference presentations, and research software, and collaborate closely with experimental and computational research partners.
The Department of Physics and Astronomy at NC State University seeks to fill the position for a Postdoctoral Research Scholar in the Lin Research Group. The scholar will advance computational studies of bimolecular structure, dynamics, interactions, and functions.
The initial appointment is for one year, with possible renewal for a second year contingent upon satisfactory performance. In the cover letter, candidates should briefly describe the project that best demonstrates their relevant expertise, their independent contributions to method, algorithm, or software development, and the connection of this work to one or more of the position’s research directions.
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